术前降钙素原、血红蛋白、中性粒细胞与淋巴细胞比值 与永久性心脏起搏器植入患者术后囊袋感染的关系研究.

Objective: To investigate the relationship between preoperative procalcitonin (PCT), hemoglobin (Hb), neutrophil-to-lymphocyte ratio (NLR) and postoperative capsular bag infection in patients with permanent pacemaker implantation (PPI). Methods: 400 patients with PPI who were admitted to the Second Affiliated Hospital of Anhui Medical University from July 2019 to July 2021 were retrospectively selected, and they were divided into infected group and non-infected group according to whether capsular bag infection occurred 1 year after surgery. Clinical data and preoperative PCT, Hb and NLR levels of patients were collected. Univariate and multivariate Logistic regression were used to analyze the influencing factors of postoperative capsular bag infection in patients with PPI, and receiver operating characteristic (ROC) curve was used to analyze the predictive value of preoperative PCT, Hb and NLR for postoperative capsular bag infection in patients with PPI. Results: After 1-year follow-up, the incidence of postoperative capsular bag infection in 400 patients with PPI was 8.00% (32/400). Multivariate Logistic regression analysis showed that increased age, diabetes mellitus, pacemaker replacement/upgrade, postoperative capsular bag hematoma, elevated PCT and NLR, reduced Hb were independent risk factors for postoperative capsular bag infection in patients with PPI (P＜0.05). ROC curve analysis showed that the area under the curve of preoperative PCT, Hb and NLR combined prediction of postoperative capsular bag infection in patients with PPI was greater than that predicted by PCT, Hb and NLR alone. Conclusion: Preoperative PCT, elevated NLR and reduced Hb are associated with postoperative capsular bag infection in patients with PPI, and the combination of preoperative PCT, Hb and NLR is of high value in predicting postoperative capsular bag infection. [ABSTRACT FROM AUTHOR]