Sentinel lymphadenectomy versus total lymphadenectomy in the staging of endometrial cancer.

Background: The Surgical staging of endometrial cancer includes a hysterectomy, bilateral salpingo-oophorectomy, and estimation of regional LN involvement, specially the pelvic and aortic lymph node. Some advised that lymphadenectomy explains the risk of recurrence and helps clinicians make the decision to give adjuvant treatment to high-risk patients. While, some suggested that, complete pelvic and para-aortic lymphadenectomy itself is associated with major comorbidities. Sentinel lymphadenectomy has been suggested in the staging process of the diseases. The aim of this study was to compare the role SLN mapping over total lymphadenectomy for detection of disease metastasis in cases of cancer of the endometrium. Method: 30 patients that were diagnosed of having endometrial cancer based on biopsy were included in this study and were divided in to two equal groups and mapping of sentinel lymph nodes was done to 15 patients and all patients had undergone lymphadenectomy. Results: In this study The mean age of patients was 55 years (range 45-74) for group 1 and was 56ys (range 43-75) for group2. Also the increase in weight as BMI, Median (Range) was 35 (26-45) for group 1 and for group2 was 34 (28-50)... And shown in our study there is no significant difference between both groups regarding BMI, age, clinical, family history and preoperative pathological results. we approved that proved that SLN biopsy has relatively equal values like lymphadenectomy in staging of endometrial cancer with sensitivity 80% and specificity 90%. Sentinel mapping had good sensitivity and specificity diagnostic potentials. [ABSTRACT FROM AUTHOR]