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Microwave-Assisted Synthesis of New Schiff Bases from Imidazo[1,2-a]pyridine-3-carbaldehyde and Aromatic Amines in PEG-400 as a Green Approach.
- Source :
-
Russian Journal of Organic Chemistry . Sep2023, Vol. 59 Issue 9, p1620-1624. 5p. - Publication Year :
- 2023
-
Abstract
- We have developed a short and highly efficient microwave-enhanced protocol for the synthesis of new Schiff bases, (E)-N-[(2-arylimidazo[1,2-a]pyridine-3-yl)methylidene]pyridin-2-amines, by the condensa-tion of 2-arylimidazo[1,2-a]pyridine-3-carbaldehydes with 2-aminopyridine in polyethylene glycol-400 as a green reaction medium in the presence of a catalytic amount of acetic acid. The essential features of this protocol are enhanced reaction rate, more eco-friendly reaction conditions, high yields, and green aspects such as avoiding toxic catalysts and hazardous organic solvents and reuse of the reaction medium. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10704280
- Volume :
- 59
- Issue :
- 9
- Database :
- Academic Search Index
- Journal :
- Russian Journal of Organic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 173766841
- Full Text :
- https://doi.org/10.1134/S1070428023090208