血浆置换与血液灌流对蜂蜇伤所致 MODS患者疗效对比.

Objective To explore the difference of therapeutic effects between plasma exchange and hemoperfusion in patients with multiple organ dysfunction syndrome (MODS) due to bee stings.Methods The clinical data of 32 patients with MODS due to bee stings in Tongliang Hospital, the First Affiliated Hospital of Chongqing Medical University from July 2015 to June 2022 were analyzed.According to the real world research method, the patients who underwent continuous venovenous hemofiltration (CVVH) combined with hemoperfusion were set as the control group (9 cases),and those who underwent CVVH combined with plasma exchange were set as the observation group (23 cases).The prognosis, hospitalization time, and changes of some inflammation and biochemical indexes before and after treatment, including C-reactive protein (CRP),white blood cell (WBC),creatine kinase isoenzyme (CK-MB),etc.,were compared and analyzed between the two groups.Results CRP,WBC,creatine kinase, CK-MB,lactate dehydrogenase, AST,ALT and creatinine in the two groups were significantly lower than those before treatment, and Cr in the observation group decreased more obviously after treatment, and the hospitalization time was shorter, with statistically significance differences (P＜0.05).There was no statistical difference in prognosis between the two groups (P＞0.05).Conclusion Both CVVH combined with plasma exchange and combined hemoperfusion therapy are effective, and CVVH combined with plasma exchange is more effective. [ABSTRACT FROM AUTHOR]