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Electrochemically enhanced peroxidase-like activity of nanohybrids for rapid and sensitive detection of H2O2 and Dopamine.
- Source :
-
Colloids & Surfaces A: Physicochemical & Engineering Aspects . Dec2023, Vol. 679, pN.PAG-N.PAG. 1p. - Publication Year :
- 2023
-
Abstract
- Longer detection times and low sensitivities are the two main drawbacks of applying colorimetric detection methods in field applications where rapid and sensitive detection is required. A discovery of the enhancement of nanozymatic activity via electrochemical means which significantly reduces the analyte detection time and enables ultra-low detection levels has been reported in this paper. A novel, simple and facile approach for the synthesis of carbon quantum dot-gold nanoparticles (CQD-AuNPs) has been developed. The CQD-AuNPs showcased catalytic activity through the oxidation of 3,3′,5,5′-Tetramethylbenzidine (TMB) in the presence of hydrogen peroxide (H 2 O 2) and followed the characteristic Michaelis-Menten equation. Surprisingly, the catalytic activity of CQD-AuNPs nanohybrids enhanced considerably while the reaction was completed under an electrochemical process and assisted the detection of H 2 O 2 and Dopamine (DA) with a limit of detection (LOD) value of 240 nM, and 0.75 μM, respectively. Most importantly, the detection time decreased by 60-fold compared to conventional nanozymatic reactions. The work covered in this paper provides a novel approach to develop the nanocomposite and a new detection technique that can be utilized across various fields of science and engineering to improve and exploit enzymatically dependent reactions. [Display omitted] • Nanozymatic activity of CQD-AuNPs to detect H 2 O 2 and dopamine has been presented. • Electrochemically enhanced nanozymatic activity of CQD-AuNPs has been reported. • The LOD value for H 2 O 2 and dopamine was 240 nM and 0.75 µM, respectively. • The proposed method was 60 times faster than the conventional nanozymatic reactions. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09277757
- Volume :
- 679
- Database :
- Academic Search Index
- Journal :
- Colloids & Surfaces A: Physicochemical & Engineering Aspects
- Publication Type :
- Academic Journal
- Accession number :
- 173630155
- Full Text :
- https://doi.org/10.1016/j.colsurfa.2023.132576