A comparative study of pregnancy outcome and risk factors in preterm premature rupture of membranes (PROM) between 28 to less than 34 weeks of gestation and 34-37 weeks of gestation.

Background: Preterm premature rupture of membranes (PPROM) is the spontaneous rupture of the fetal membranes before the completion of 37 weeks of pregnancy. PPROM is one of the most common complications of pregnancy. It is an important cause of perinatal morbidity and mortality. PPROM occurs in 3% of pregnancies. Aims and objectives: The present study was done to identify risk factors associated with PPROM and feto-maternal outcome in PPROM. Methods: The present study was single centered prospective comparative study. A total of 100 patients in each group that is GROUP A - 28 to less than 34 weeks of gestation and GROUP B-34 to 37 weeks of gestation were selected for the study. Study was conducted from April 2019 to March 2020 in the Department of obstetrics and Gynecology, Nil Ratan Sircar medical college and hospitals, Kolkata, West Bengal, India. Statistical data were analysed by using Microsoft Excel and SPSS V.20 software. Results: PPROM is mainly seen is in primigravida patients compared to multigravida. My study had 60% primigravida in Group A and 52% in Group B. There were no risk factors found in 74% patient in 28 to less than 34 weeks of gestation and 76% in 34-37 weeks of gestation. Most common risk factors in both groups was history of PPROM in previous pregnancy followed by malpresentation like Breech. Perinatal mortality includes stillbirth and early neonatal death which was 12% in Group A and 2% in Group B. Maternal morbidity was less in both groups. There was no maternal mortality. Chorioamnionitis was seen in 3 patients in Group A. Conclusion: Perinatal morbidity was mainly due to respiratory distress syndrome and prematurity in less than 34 weeks of gestation. Maternal morbidity was also increased mainly in lower gestational age group. [ABSTRACT FROM AUTHOR]