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СИНТЕЗ И АНАЛИЗ КОМПЛЕКСНОГО СОЕДИНЕНИЯ НА ОСНОВЕ ИОНОВ Сo(II) И НОРФЛОКСАЦИНА.

Authors :
РАСУЛОВ, А. А.
ЕШИМБЕТОВ, А. Г.
АШУРОВ, Ж. М.
ИБРАГИМОВ, Б. Т.
Source :
Uzbek Chemical Journal / O'Zbekiston Kimyo Jurnali. 2023, Issue 4, p10-17. 8p.
Publication Year :
2023

Abstract

Background. The creation of safe and highly effective drugs in pharmacology is relevant. These include the bactericidal norfloxacin, from the group of fluoroquinolones. It is used for infections of the prostate, digestive and urinary systems. Work is underway to synthesize new compounds based on it. Purpose: synthesis of a new biologically active compound - a metal complex with norfloxacin, determination of its structure. Methodology. The method of X-ray crystallography (Xcalibur R Oxford Diffraction diffractometer) at room temperature and IR spectroscopy (IRTracer-100 from Shimadzu, Japan) were used. Originality. The crystal structure and molecular characteristics of a new mixed-ligand complex were obtained for the first time. Findings. A new mixed-ligand complex [Co(HL)2(H2O)2](CH3COO)Cl(H2O)2 was obtained, and its molecular characteristics and crystal structure were determined by X-ray crystallography. [ABSTRACT FROM AUTHOR]

Details

Language :
Russian
ISSN :
00421707
Issue :
4
Database :
Academic Search Index
Journal :
Uzbek Chemical Journal / O'Zbekiston Kimyo Jurnali
Publication Type :
Academic Journal
Accession number :
173505943