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Detection and tracking of cytoplasmic G-quadruplexes in live cells.
- Source :
-
Chemical Communications . 11/18/2023, Vol. 59 Issue 89, p13348-13351. 4p. - Publication Year :
- 2023
-
Abstract
- A TTPP probe was developed to distinguish G-quadruplexes (G4s) from other nucleic acid topologies through longer fluorescence lifetimes and higher quantum yields. In fluorescence lifetime imaging microscopy, TTPP enabled the visualization of cytoplasmic G4s in live cells, and showed the potential to detect cell apoptosis and ferroptosis by tracking cytoplasmic G4s. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 13597345
- Volume :
- 59
- Issue :
- 89
- Database :
- Academic Search Index
- Journal :
- Chemical Communications
- Publication Type :
- Academic Journal
- Accession number :
- 173475506
- Full Text :
- https://doi.org/10.1039/d3cc03043a