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Myofibroblastoma in the Liver: A Case Report and Review of Literature.

Authors :
Narasimhamurthy, Mohan
Savant, Deepika
Shreve, Lauren
Rosen, Mark A.
Lee, Major Kenneth
Cooper, Kumarasen
Furth, Emma E.
Zhang, Paul J.
Yang, Zhaohai
Source :
International Journal of Surgical Pathology. Dec2023, Vol. 31 Issue 8, p1559-1564. 6p.
Publication Year :
2023

Abstract

Myofibroblastoma is a rare benign mesenchymal tumor first described in the breast. It is also known as mammary-type myofibroblastoma outside of the breast, more frequently located along the embryonic milk line. Exceptionally, myofibroblastoma can occur at visceral locations. We present a case of myofibroblastoma detected incidentally in the liver. A well-circumscribed mass, grossly measuring 6.2 cm in the liver parenchyma, was found on imaging studies. Histologically, the lesion is characterized by benign spindle cells in a hyalinized collagenous stroma, with positive staining for SMA and ER, focal positivity for CD34, negative for desmin, and loss of RB1. This rare tumor at such an unusual location makes it diagnostically challenging, especially on core biopsy of the lesion. To our knowledge, this is the second case of myofibroblastoma in the liver reported in the English literature and the first such case with a detailed pathology description. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
10668969
Volume :
31
Issue :
8
Database :
Academic Search Index
Journal :
International Journal of Surgical Pathology
Publication Type :
Academic Journal
Accession number :
173345830
Full Text :
https://doi.org/10.1177/10668969231160262