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Versatile RNA: overlooked gems of the transcriptome.

Authors :
Erdem, Murat
Cicek, Mustafa
Erson‐Bensan, Ayse Elif
Source :
FEBS Journal. Oct2023, Vol. 290 Issue 20, p4843-4851. 9p.
Publication Year :
2023

Abstract

The critical role of RNA, its use and targetability concerning different aspects of human health are gaining more attention because our understanding of the versatility of RNA has dramatically evolved over the last decades. We now appreciate that RNA is far more critical than a messenger molecule and possesses many complicated functions. As a multifunctional molecule with its sequence, flexible structures and enzymatic abilities, RNA is genuinely powerful. Mammalian transcriptomes consist of a dynamically regulated plethora of coding and noncoding RNA types. However, some aspects of RNA metabolism remain to be explored. In this Viewpoint, we focus on the transcriptome's unconventional and possibly overlooked aspects to emphasize the importance of RNA in mammalian systems. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
1742464X
Volume :
290
Issue :
20
Database :
Academic Search Index
Journal :
FEBS Journal
Publication Type :
Academic Journal
Accession number :
173053890
Full Text :
https://doi.org/10.1111/febs.16742