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Development of a mobile laboratory system in hydrogen fuel cell buses and evaluation of the performance for COVID-19 RT-PCR testing.

Authors :
Okude, Miho
Suzuki, Kenji
Naito, Asami
Ebashi, Akio
Kusama, Tomoka
Kiyotaki, Junichi
Akashi, Yusaku
Kiyasu, Yoshihiko
Kurihara, Yoko
Notake, Shigeyuki
Takanashi, Masaki
Setoyama, Tomokazu
Kawakami, Yasushi
Suzuki, Hiromichi
Source :
Scientific Reports. 10/16/2023, Vol. 13 Issue 1, p1-8. 8p.
Publication Year :
2023

Abstract

We designed and developed two new types of hydrogen fuel cell (HFC) buses (motorcoach and minibus) with a mobile laboratory system. Feasibility studies have been performed for mobile laboratory testing, particularly for the laboratory performance of COVID-19 RT-PCR (PCR). We evaluated the driving range capability, PCR sample size capacity, turnaround time (TAT), and analytical performance for the detection of SARS-CoV-2. Saliva samples were used for the current study, and the analytical performance was compared with that of the reference PCR. The estimated driving range and sample size capacity of the HFC and HFC minibus were 432 km and 2847 samples, respectively, for the HFC motorcoach and 313 km and 1949 samples for the HFC minibus. For the TAT, the median time between sample submission and completion of PCR was 86 min for the motorcoach and 76 min for the minibus, and the median time between sample submission and electronic reporting of the result to each visitor was 182 min for the motorcoach and 194 min for the minibus. A secondary analysis of 1574 HFC mobile laboratory testing samples was conducted, and all negative samples were found to be negative by reference PCR. Furthermore, all samples were confirmed to be positive by reference PCR or other molecular examinations. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
20452322
Volume :
13
Issue :
1
Database :
Academic Search Index
Journal :
Scientific Reports
Publication Type :
Academic Journal
Accession number :
173034569
Full Text :
https://doi.org/10.1038/s41598-023-44925-7