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免疫检查点抑制剂联合方案治疗 转移性尿路上皮癌的研究进展.

Authors :
刘建兵
岳中瑾
尚攀峰
刘雅婷
常宏
Source :
Journal of New Medicine. Sep2023, Vol. 54 Issue 9, p611-617. 7p.
Publication Year :
2023

Abstract

Metastatic urothelial carcinoma (mUC) yields poor prognosis and is diffi cult to treat. Immunotherapy strategies have developed rapidly in recent years, and clinical prognosis of mUC patients has been significantly improved. However, immune checkpoint inhibitors (ICIs) alone have limited efficacy, and some ICIs monotherapy indications for mUC have also been withdrawn in recent years. Therefore, combined therapy based on ICIs has become a research hotspot in the treatment of mUC. At present, multiple clinical studies of ICIs combined with chemotherapy, antibody-drug conjugates, and dual immunotherapy for multiple lines of treatment of mUC have proved that combined therapy possesses promising development prospect. In this article, latest progress in ICIbased combined treatment for mUC was reviewed, aiming to provide reference for clinicians. [ABSTRACT FROM AUTHOR]

Details

Language :
Chinese
ISSN :
02539802
Volume :
54
Issue :
9
Database :
Academic Search Index
Journal :
Journal of New Medicine
Publication Type :
Academic Journal
Accession number :
173023903
Full Text :
https://doi.org/10.3969/j.issn.0253-9802.2023.09.001