Inflammatory Bowel Disease-Mimicking Colitis Associated With Nintedanib-Based Therapy in a Lung Cancer Patient.

Keywords: nintedanib; inflammatory bowel disease mimic; nintedanib-associated colitis; lung cancer therapy; inflammatory bowel disease EN nintedanib inflammatory bowel disease mimic nintedanib-associated colitis lung cancer therapy inflammatory bowel disease 1326 1328 3 10/10/23 20231001 NES 231001 Nintedanib is a competitive nonreceptor and receptor tyrosine kinase inhibitor used for the treatment of interstitial lung diseases and non-small-cell lung carcinomas. Ultimately, based on an integrative review of all clinical and histologic features, a working diagnosis of nintedanib-associated inflammatory bowel disease-mimicking chronic active colitis was favored over inflammatory bowel disease or other drug-induced injury.[4] Subsequently, the docetaxel-nintedanib therapy was stopped, and the diarrheal symptoms regressed in the following weeks. [Extracted from the article]