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The Search for Domestic Pharmaceutical Substances among Metal Complexes Based on (Hetero)arylamides of 4-Aryl-2-hydroxy-4-oxo-2-butenoic Acids.
- Source :
-
Russian Journal of Coordination Chemistry . Oct2023, Vol. 49 Issue 10, p672-679. 8p. - Publication Year :
- 2023
-
Abstract
- The data obtained on the synthesis and search for biological activity among metal complexes based on 4-aryl-2-hydroxy-4-oxo-2-butenoic acid (hetero)arylamides were integrated. The data on the antimicrobial, anti-inflammatory, analgesic, hypoglycemic, antihypoxic, and immunotropic activities of the synthesized compounds were analyzed. The relationship between the chemical structure and biological activity of chelate complexes was discussed and some regular features were identified. Promising compounds for further research and development of new domestic pharmaceutical substances were found. [ABSTRACT FROM AUTHOR]
- Subjects :
- *BIOSYNTHESIS
*CHEMICAL synthesis
*MORPHOLOGY
*CHEMICAL structure
*ACIDS
Subjects
Details
- Language :
- English
- ISSN :
- 10703284
- Volume :
- 49
- Issue :
- 10
- Database :
- Academic Search Index
- Journal :
- Russian Journal of Coordination Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 172807296
- Full Text :
- https://doi.org/10.1134/S1070328423600584