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Programming therapeutic probiotics by self-tunable sense-and-respond genetic circuits.
- Source :
-
Trends in Microbiology . Nov2023, Vol. 31 Issue 11, p1099-1101. 3p. - Publication Year :
- 2023
-
Abstract
- Probiotics can be programmed to sense and respond to intracellular disease signals to deliver the desired therapeutic effectors. The sense-and-respond genetic circuits, especially self-tunable ones, hold promise in improving the precision, effectiveness, and intelligence of therapeutic activities. Here, we present notable advances in the creation of engineered probiotics that harbour sense-and-respond genetic circuits. [ABSTRACT FROM AUTHOR]
- Subjects :
- *PROBIOTICS
*SYNTHETIC biology
Subjects
Details
- Language :
- English
- ISSN :
- 0966842X
- Volume :
- 31
- Issue :
- 11
- Database :
- Academic Search Index
- Journal :
- Trends in Microbiology
- Publication Type :
- Academic Journal
- Accession number :
- 172778437
- Full Text :
- https://doi.org/10.1016/j.tim.2023.08.001