非稳态负荷评估方法的研究进展.

Allostatic load (AL) is a comprehensive index reflecting the cumulative wear status of multiple physiological systems, which can significantly predict the physical and mental healtli of individuals. The evaluation of AL includes quantitative and qualitative methods, with quantitative approaches being more commonly utilized. However, there exists considerable heterogeneity in the selection and calculation methods of biomarkers when determining the allostatic load index (ALI). Some AL studies do not contain biomarkers of neuroendocrine system, which is not consistent with its original conceptual framework. Currently, numerous ALI calculation methods are employed, with the high-risk quartile method being the most prevalent, yet this restricts the comparability of cross-sample research outcomes. Each calculation method has its own advantages and disadvantages. Therefore, the purpose of this paper is to review the selection of bio markers and ALI calculation methods in the evaluation of AL and its influence on the research results. The purpose of this study is to provide a reference for the selection of biomarkers and index calculation methods in future AL research. [ABSTRACT FROM AUTHOR]