Allogeneic peripheral stem-cell transplantation with reduced-intensity conditioning regimen in refractory primary B-cell prolymphocytic leukemia: a long-term follow-up.

The article presents a follow-up of a case of refractory primary B-cell prolymphocytic leukemia (B-PLL) treated with allogeneic stem-cell transplantation with reduced-intensity conditioning fludarabine-based regimen. In April 2001, warm-antibody hemolytic anemia was diagnosed and treated with steroids leading to a complete remission. In January 2002, the patient was hospitalized because of clinically symptomatic idiopathic thrombocytopenia, resistant to immunoglobulin and steroids. Consequently, the patient underwent splenectomy with full and durable recovery of platelets.