SERUM URIC ACID LEVELS AND CARDIOVASCULAR OUTCOMES IN ACUTE CORONARY SYNDROME- 30 DAY FOLLOW UP.

Coronary artery disease is a leading cause of morbidity and mortality globally. Various risk factors for the development of cardiovascular disease are known, however, the role of uric acid has been debatable. Patients more than 40 years of age diagnosed as Acute Coronary Syndrome were admitted and observed for in hospital course, in-hospital mortality and then were followed up at 30 days after discharge. The patients were stratified according to uric acid level as normouricemia and hyperuricemia and the observations were made. We found that hyperuricemia was seen more in patients with diabetes, dyslipidemia, obesity and smokers. Inhospital course was more complicated in patients with hyperuricemia.Heart failure, arrhythmias, cardiogenic shock and in-hospital mortality were significantly higher in hyperuricemic patients. Hyperuricemia was also associated with more severe coronary artery disease. 30 day MACE rate was significantly higher in patients with baseline hyperuricemia driven mainly by cardiovascular death and reinfarction. [ABSTRACT FROM AUTHOR]