Synthesis of Fluorescent Cu-MOF and Ni-MOF Sensors for Selective and Sensitive Detection of Arginine and Hydrogen Sulfide.

In this work, we have synthesized a vinyl functional group containing 4, 4′-bis (1, 3-diphenoxypropane) diacrylic acid organic linker, which was used in construction of novel Cu-MOF (1) and Ni-MOF (2) through a solvothermal method. The synthesized MOFs were characterized by FT-IR, PXRD, TGA, FE-SEM, and EDAX. In particular, Cu-MOF can be used as a bifunctional sensor for detection of arginine and H2S by a fluorescence "turn-off" mechanism with low limit of detection of 0.5 µM and 3.1 µM with quick response time (< 1 min) respectively. On the other hand, Ni-MOF demonstrated to have capability for selective detection of H2S only by quenching mechanism in the presence of various other biologically important analytes. The limit of detection was found to be 3.0 µM and showed rapid quenching in fluorescence intensity (< 1 min). Organic linker 4,4′-bis(1,3-diphenoxypropane) diacrylic acid was used to construct Cu-MOF and Ni-MOF, which are showing good selectivity and sensitivity towards arginine and H2S using turn- off quenching mechanism. [ABSTRACT FROM AUTHOR]