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Diagnóstico de alergia inmediata para penicilina: estudio piloto.

Authors :
Armenta-Morales, Julinela
Ruiz-Sánchez, Dulce Mariel
Rivero-Yeverino, Daniela
Papaqui-Tapia, José Sergio
Rios-López, Juan Jesús
Lopez-Garcia, Aida Inés
Caballero-López, Chrystopherson
Pacheco-Jiménez, Yosahandi
Source :
Revista Alergia de Mexico. Jul-Sep2023, Vol. 70 Issue 3, p191-191. 1p.
Publication Year :
2023

Abstract

Objectives: To confirm the presence of allergy to penicillin and amoxicillin by in vivo exposure tests in patients with a history of immediate reaction to these drugs. Methods: Observational, cross-sectional, descriptive and prolective study. Patients between 12 and 60 years old with a history of immediate reaction after administration of penicillin and/or amoxicillin were included. Skin prick and intradermal tests were performed with benzylpenicilloyl polylysine and penicillin G, as well as oral challenge with amoxicillin. Results: Ten female and 3 male patients were included. The mean age was 39 years. In 84.6% of the cases the last adverse drug reaction occurred 10 years ago and in all cases it manifested with urticaria. Allergy to penicillin was corroborated in only 38.4% of cases. The most frequent adverse reaction after in vivo exposure tests was pruritus in 23%. Conclusions: Patients with suspected penicillin allergy should be evaluated by in vivo exposure testing with major and minor determinants to corroborate or rule out allergic reactions and improve treatment conditions. [ABSTRACT FROM AUTHOR]

Details

Language :
Spanish
ISSN :
00025151
Volume :
70
Issue :
3
Database :
Academic Search Index
Journal :
Revista Alergia de Mexico
Publication Type :
Academic Journal
Accession number :
172262993
Full Text :
https://doi.org/10.29262/ram.v70i3.1261