Interplay between host and Candida albicans during commensal gut colonization.

C. albicans colonization affects the gut-brain axis Impacts of the gut microbiota on the brain through the gut-brain axis have recently become the subject of investigation. The gut-brain axis is defined as the bidirectional communication between the brain and the gastrointestinal tract through direct and indirect pathways including direct neuronal innervation of the intestines, metabolic pathways, and immune system modulation. I albicans i colonization changed the gut metabolite environment in a way that reduced I C i . I albicans i is not the only organism to affect susceptibility to bacterial infection or signaling in the gut-brain axis. [Extracted from the article]