Preparation And Evaluation Of New Polyherbal Formulation Their For Wound Healing Activity.

Herbal medicine (also herbalism) is the study of pharmacognosy and the use of medicinal plants, which are a basis of traditional medicine. Any damage or break in the surface of the skin is wound. It may be defined as a loss or breaking of cellular, anatomical and functional continuity of living tissue In Soxhlet extraction, solvent extraction was performed which involves extraction with solvents of increasing polarity from a nonpolar to a more polar solvent to ensure that a wide polarity range of compound can be extracted. 1 % of extract was incorporated in preparation of gel formulation using Carbomer 940polymer as gelling agent. Three formulae 1, 2 and 3 of gel containing varying concentrations of Carbomer 940(0.5, 1 and 1.5%) were prepared. Carbomer 940 was soaked in distilled water overnight. Selected extracts were dissolved in ethanol. Different Physicochemical evaluation parameters of formulated ointments were examined by standard methods and results were found within the acceptable limits. Cissampelos Pareira Vein-islet number/mm² was 3.6 and it ranges from 3.5 to 3.9. the Palisade ratio was 3 and it ranges from 2.75 to 3.75. The Stomata length (µm) was found to be 20.5 and it ranges from 18.1 to 22.7. Hence we can conclude from our findings that the developed formulations containing bioactive Methanol extracts of Cissampelos Pareira and Bergenia ciliate formulation were found to be acting on each component of wound healing process. [ABSTRACT FROM AUTHOR]