A REVIEW ON ANALYTICAL METHODS FOR INDIVIDUAL AND SIMULTANEOUS ANALYSIS OF ALISKIREN AND VALSARTAN.

Aliskiren is referred to as a direct renin inhibitor. renin catalysis the conversion of angiotensinogen to angiotensin-1 Aliskiren and Valsartan use as hypertension. Valsartan belongs to the angiotensin 2 receptor blocker family. Which prevent the protein angiotensin 2. Cardiac stimulation and renal reabsorption of sodium. This review article represents the collection and discussion of various analytical methods available in the literature for the determination of Aliskiren and Valsartan in pharmaceutical and biological samples consisting of UV spectroscopy, RP-HPLC, HPTLC, LCMS/MS methods. The anticipated review provides details about the comparative utilization of various analytical techniques for the determination of Aliskiren and Valsartan alone and in combination. The present review article can be effectively explored to conduct future analytical investigation for the estimation of Aliskiren and Valsartan. [ABSTRACT FROM AUTHOR]