Methanol/acetone treatment helps the amplification of FMR1 CGG repeat fragment in dried blood spots from Guthrie cards.

Presents research which developed a method for the identification of fragile X syndrome. The syndrome causing intellectual disability resulting from an absence of the protein FMR1; Populations affected by the condition; Cytogenic findings; Methods and results; Screening for male fragile X syndrome using Guthrie dried blood-spot samples.