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Body mass index does not impact survival in COVID-19 patients requiring veno-venous extracorporeal membrane oxygenation.
- Source :
-
Perfusion . Sep2023, Vol. 38 Issue 6, p1174-1181. 8p. - Publication Year :
- 2023
-
Abstract
- Introduction: With the increased demand for veno-venous extracorporeal membrane oxygenation (VV ECMO) during the COVID-19 pandemic, guidelines for patient candidacy have often limited this modality for patients with a body mass index (BMI) less than 40 kg/m2. We hypothesize that COVID-19 VV ECMO patients with at least class III obesity (BMI ≥ 40) have decreased in-hospital mortality when compared to non-COVID-19 and non-class III obese COVID-19 VV ECMO populations. Methods: This is a single-center retrospective study of COVID-19 VV ECMO patients from January 1, 2014, to November 30, 2021. Our institution used BMI ≥ 40 as part of a multi-disciplinary VV ECMO candidate screening process in COVID-19 patients. BMI criteria were not considered for exclusion criteria in non-COVID-19 patients. Univariate and multivariable analyses were performed to assess in-hospital mortality differences. Results: A total of 380 patients were included in our analysis: The COVID-19 group had a lower survival rate that was not statistically significant (65.7% vs.74.9%, p =.07). The median BMI between BMI ≥ 40 COVID-19 and non-COVID-19 patients was not different (44.5 vs 45.5, p =.2). There was no difference in survival between the groups (73.3% vs. 78.5%, p =.58), nor was there a difference in survival between the COVID-19 BMI ≥ 40 and BMI < 40 patients (73.3, 62.7, p =.29). Multivariable logistic regression with the outcome of in-hospital mortality was performed and BMI was not found to be significant (OR 0.99, 95% CI 0.89, 1.01; p =.92). Conclusion: BMI ≥ 40 was not an independent risk factor for decreased in-hospital survival in this cohort of VV ECMO patients at a high-volume center. BMI should not be the sole factor when deciding VV ECMO candidacy in patients with COVID-19. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ADULT respiratory distress syndrome treatment
*OBESITY
*STATISTICS
*KRUSKAL-Wallis Test
*COVID-19
*CONFIDENCE intervals
*MULTIVARIATE analysis
*EXTRACORPOREAL membrane oxygenation
*RETROSPECTIVE studies
*ACQUISITION of data
*HOSPITAL mortality
*SEVERITY of illness index
*COMPARATIVE studies
*MEDICAL records
*DESCRIPTIVE statistics
*BODY mass index
*LOGISTIC regression analysis
*ODDS ratio
*DATA analysis software
*BLOOD filtration
Subjects
Details
- Language :
- English
- ISSN :
- 02676591
- Volume :
- 38
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- Perfusion
- Publication Type :
- Academic Journal
- Accession number :
- 171102955
- Full Text :
- https://doi.org/10.1177/02676591221097642