HIGH DOSE OF TRANEXAMIC ACID TO TREAT MASSIVE POSTPARTUM HAEMORRHAGE DUE TO COAGULOPATHY INDUCED BY POISONOUS SNAKE BITE IN PREGNANT WOMAN: A NEAR MISS MATERNAL DEATH--A CASE REPORT.

Snake bite is a rare event during pregnancy. Extensive coagulation abnormalities and fibrinolytic dysfunction is observed following snakebite. Snake bite leads to miscarriages, preterm birth, antepartum haemorrhage, intrauterine foetal death (IUFD), coagulation failure which progress to postpartum haemorrhage (PPH) and early neonatal death. We present a 27-year-old unbooked G4P3L2 woman at 30 weeks gestation with snake bite and IUFD. Systemic coagulopathy leads to massive PPH after delivery. Until blood and blood products were available, the mother was managed by a multidisciplinary team and treated with high dose of tranexamic acid. In resource constrained setting, disseminated intravascular coagulopathy (DIC) arising from systemic envenomation due to snake bite in pregnancy could be challenging. Obstetric outcome depends on the degree of envenomation, gestational age at presentation, timing, duration, and quality of treatment. [ABSTRACT FROM AUTHOR]