The superiority of combining Chinese medicinals for promoting blood circulation and removing blood stasis with antiplatelet drugs in the secondary prevention of coronary heart disease.

Antiplatelet drugs such as aspirin and clopidogrel are the cornerstones of the secondary prevention of coronary heart disease ( CHD), which can significantly improve treatment outcomes; however, long-term use increases the risk of bleeding and drug resistance. Recent clinical studies have shown that the combination of Chinese medicinals for promoting blood circulation and removing blood stasis with antiplatelet drugs has further reduced the disability rate and mortality of patients with CHD without increasing the risk of bleeding, but the evidence needs to be further strengthened for clinical application. Therefore, to achieve the secondary prevention of CHD, it is important to expand the clinical and mechanistic studies on the prevention and treatment of CHD with Chinese medicinals for promoting blood circulation and removing blood stasis combined with antiplatelet drugs according to the requirements of evidence-based medicine,objectively evaluating its efficacy and safety advantages, and exploring its biological mechanism. [ABSTRACT FROM AUTHOR]