Dose reductions in immunoglobulin replacement are associated with increased antibiotic usage in patients with antibody deficiency.

.83</td></tr></tbody></table> ht 1 Abbreviations: IgG, immunoglobulin G; IgRT, immunoglobulin replacement therapy; IQR, interquartile range. We demonstrate that, in previously stable patients, IgRT dose reductions lead to a reduction in trough IgG, which is associated with an increased frequency of infections requiring outpatient antibiotic use. [Extracted from the article]