Divergent Fluorinations of Vinylcyclopropanes: Ring‐Opening 1,5‐Hydrofluorination and Ring‐Retaining 1,2‐Difluorination.

Organofluorine compounds have been widely used in pharmaceutical, agrochemical, and material sciences. Reported herein are divergent fluorination reactions of vinylcyclopropanes with different electrophiles, which allow the facile synthesis of homoallylic monofluorides and vicinal‐difluorides through ring‐opening 1,5‐hydrofluorination and ring‐retaining 1,2‐difluorination, respectively. Both protocols feature mild conditions, simple operations, good functional group tolerance, and generally good yields. The practicality of these reactions is demonstrated by their scalability, as well as the successful conversion of the formed homoallylic monofluorides into other complex fluorinated molecules. [ABSTRACT FROM AUTHOR]