Clinical association of hepatic impairment with dengue infection outcomes in children at tertiary care center.

Background: Dengue virus infection has become a major public health concern in recent years due to an increase in its complex and unusual symptoms. Hepatomegaly increased liver enzymes to fulminant hepatic failure are just a few of the diverse signs of dengue's hepatic involvement. Material and Methods: At the Department of Paediatrics, Vishwanharathi Medical College & General Hospital, R T Nagar Near Penchikalapadu, Kurnool, Andhra Pradesh, India, this was the prospective Cohort Study that was planned. The study used 50 people who were treated with a Dengue infection and had a positive test for Dengue. Patients with a Dengue Sero positive are chosen and checked for hepatomegaly and jaundice. They also get a full blood count, Liver function tests, and an ultrasound of the abdomen, PT, APTT, HBsAg, HCV and Widal. Study was done between February 2022 to January 2023. Results: Early detection of dengue's hepatic dysfunction could help determine how serious the condition is. Massive hemorrhage and other life-threatening consequences could be avoided with early management. Future research should test the role of hepatoprotective medications in dengue to promote early recovery and lower morbidity and mortality. Conclusion: There have been various reports of dengue outbreaks increasing hepatic involvement in emerging nations like India. Early detection of hepatic dysfunction should help to prevent lifethreatening consequences because it is temporary and reversible in dengue. [ABSTRACT FROM AUTHOR]