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Vitamin D levels have a potential role in predicting the disease severity in COVID-19 positive pediatric patients.
- Source :
-
Biomedica . 3/31/2023, Vol. 39 Issue 1, p33-33. 1p. - Publication Year :
- 2023
-
Abstract
- Background and Objective: The contagious and invasive nature has made coronavirus disease-19 (COVID-19) a critical health issue for the community. The lower respiratory tract is the major site of inflammation seen in COVID-19-positive individuals. Vitamin D (Vit D) has been proposed to have a positive role in immunomodulation, hence, this study aimed to determine the association between Vit D levels and the severity of COVID-19 in infected pediatric patients presenting at a secondary healthcare hospital in Pakistan. Methods: This cross-sectional analytical study was conducted on 100 pediatric patients of the age range 1-18 years from March to December 2021. These patients were hospitalized and diagnosed with coronavirus disease with confirmed results on a real-time reverse transcription-polymerase chain reaction. Blood samples of the patients were taken to monitor the baseline levels of markers of acute infection and Vit D levels. Patients with serum Vit D levels ≤ 20ng/ml were labeled with deficiency, those with levels 21-29ng/ml were presumed to have Vit D insufficiency whereas levels ≥30 ng/ml were considered normal. Results: There were 57 (57%) males and 43 (43%) female pediatric patients. The mean age of the patients was 10.46 ± 4.25 years (1-18 years). The deficient Vit D level group had a greater frequency of pyrexia, weakness, cough, anosmia, headache, myalgia, and diarrhea. The levels of Vit D and severity of the disease were significantly associated (p-value = 0.027). Conclusion: Pediatric patients with COVID-19 having optimum levels of Vit D were less likely to develop complications associated with the severity of the disease. [ABSTRACT FROM AUTHOR]
- Subjects :
- *CHILD patients
*VITAMIN D
*COVID-19
*FEVER
*COUGH
*WOMEN patients
Subjects
Details
- Language :
- English
- ISSN :
- 19924852
- Volume :
- 39
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Biomedica
- Publication Type :
- Academic Journal
- Accession number :
- 169790729
- Full Text :
- https://doi.org/10.24911/biomedica/5-880