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MOYAMOYA disease in an adolescent with HIV-1.
- Source :
-
Oxford Medical Case Reports . Jun2023, Vol. 2023 Issue 6, p1-3. 3p. - Publication Year :
- 2023
-
Abstract
- Moyamoya disease has been reported in both children and adults with HIV-1. Most cases reported in children were found to have unsuppressed viral loads and low CD4 counts. Although the aetiology of the disease is largely unknown, a few studies have postulated cytokine imbalance and immune activation as possible causes. Intimal staining of the involved cerebral arteries have revealed transmembrane glycoprotein of HIV-gp 41. We present the case of an 18-year-old boy with congenitally acquired HIV-1 who presented with right hemiparesis at the age of 12 years and was found to have Moyamoya disease on neuroimaging. His CD4 count has always been low (<100 cells/cumm) in spite of being virally suppressed. He was started on anti-retroviral therapy at 5 and half years of age and he was continued on the same. He was treated conservatively and he continues to have residual right hemiparesis. [ABSTRACT FROM AUTHOR]
- Subjects :
- *MOYAMOYA disease
*HIV
*ETIOLOGY of diseases
*VIRAL load
*ANTIRETROVIRAL agents
Subjects
Details
- Language :
- English
- ISSN :
- 20538855
- Volume :
- 2023
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- Oxford Medical Case Reports
- Publication Type :
- Academic Journal
- Accession number :
- 166742731
- Full Text :
- https://doi.org/10.1093/omcr/omad065