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Successful ART outcome in a woman with McCune-Albright syndrome: a case report and literature review.

Authors :
Pirtea, Paul
Heggarty, Estelle
Hagege, Estelle
Tran, Chloe
de Ziegler, Dominique
Farabet, Clemence
Filali, Meryem
Poulain, Marine
Ayoubi, Jean Marc
Source :
Journal of Assisted Reproduction & Genetics. Jul2023, Vol. 40 Issue 7, p1669-1675. 7p.
Publication Year :
2023

Abstract

McCune-Albright syndrome (MAS) is a rare genetic disease affecting multiple organs, including endocrine tissues. This endocrinopathy is sometimes responsible for infertility, as it may induce an independent functioning of the ovaries leading to anovulatory cycles. This case report describes the infertility journey of a 22-year-old female who had early puberty and irregular periods with high estrogen and progesterone levels, low FSH and LH (on day 3 of her menstrual cycle), and a multi-cystic right ovary. She received several infertility treatments: initially in vitro oocyte maturation (IVM) followed by cyst transvaginal ultrasound-guided aspiration, all unsuccessful. A right hemi-ovariectomy was performed that eventually restored regular cycles and made it possible to perform ovarian stimulation (OS) and in vitro fertilization (IVF). Live birth was obtained after the first embryo transfer. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
10580468
Volume :
40
Issue :
7
Database :
Academic Search Index
Journal :
Journal of Assisted Reproduction & Genetics
Publication Type :
Academic Journal
Accession number :
164971248
Full Text :
https://doi.org/10.1007/s10815-023-02844-6