上海市嘉定区糖尿病患者视网膜病变发病情况分析.

Objective To investigate the occurrence and distribution of diabetic retinopathy （DR) in patients with diabetes in Jiading District, Shanghai. Methods DR examination was conducted in 13 communities of the jurisdiction for the patients with type 2 diabetes in 2017, and DR follow-up examination was regularly organized from 2018 to 2021, and new patients entered the follow-up cohort every year from 2018 to 2021. Finally, the 4-year cumulative incidence and incidence density of patients with retinopathy were calculated. DR examination included vision examination, computer optometry, fundus film, etc. Results A total of 13 184 diabetic patients participated in DR screening in 2017, and annual follow-up examinations were conducted from 2018 to 2021. A total of 8 758 patients were included in the cumulative incidence statistics. During the 4-year follow-up period，937 patients developed DR lesions, with acumulative incidence of 10.70% and an annual average incidence of 2.68%. The cumulative incidence of male （10.85%) was slightly higher than that of female （10.56%). The cumulative incidence decreased with the increase of age group without statistic difference. The patients enrolled in 2017 who participated in DR screening and did not detect DR lesions were followed up annually from 2018 to 2021, and the newly added patients were followed up from 2018 to 2021. The number of cases finally included in the incidence density statistics was 10 253. After 4 years of follow-up, the incidence density of DR in diabetic patients was 34.20/1 000 person-years. The incidence density was 35.54/1 000 person-years for males and 33.03/ 1000 person-years for females. Cox regression analysis showed that male （HR=1.278，95%CI：1.120- 1.458) diabetic patients were more likely to develop DR, and better naked eye vision （HR=0.373，95%CI： 0.172-0.809) was a protective factor for the development of DR in diabetic patients. Conclusion The incidence of DR in diabetic patients is relatively high in Jiading District, Shanghai. While the response rate of regular follow-up is relatively low. It is necessary to strengthen the publicity, carry out regular DR screening in diabetic patients, and focus on male, poor naked eye vision diabetic patients. [ABSTRACT FROM AUTHOR]