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Prevalence of five treatable sexually transmitted infections among women in Lower River region of The Gambia.

Authors :
Butcher, Robert
Jarju, Sheikh
Obayemi, Dolapo
Bashorun, Adedapo Olufemi
Vasileva, Hristina
Bransbury-Hare, Hannah
Agboghoroma, Orighomisan
Drammeh, Lamin
Holland, Martin
Harding-Esch, Emma
Clarke, Ed
Source :
BMC Infectious Diseases. 7/13/2023, Vol. 23 Issue 1, p1-8. 8p.
Publication Year :
2023

Abstract

Background: The prevalence of sexually transmitted infections (STIs) in sub-Saharan Africa is poorly described. We aimed to determine the prevalence of five treatable STIs (Chlamydia trachomatis, Neisseria gonorrhoeae, Trichomonas vaginalis, Mycoplasma genitalium, Treponema pallidum) in a sample of Gambian women from the general population. Methods: Archived specimens from 420 women aged 15 − 69 years living in The Gambia enrolled in a clinical trial of human papilloma virus vaccine schedules were tested in this study. Urine samples were tested for C. trachomatis, N. gonorrhoeae, T. vaginalis and M. genitalium using a commercially available, open-platform multiplex PCR kit. A fragment of the ompA gene was amplified from C. trachomatis-positive samples and sequenced. Serum samples were tested for T. pallidum using the Chembio DPP Syphilis Screen and Confirm test. Results: Overall, 41/420 (9.8%) women tested positive for at least one STI. 32 (7.6%), 9 (2.1%), 1 (0.2%), 1 (0.2%) and 0 (0.0%) tested positive for T. vaginalis, C. trachomatis, N gonorrhoeae, M. genitalium and T. pallidum, respectively. ompA gene sequence was available from five C. trachomatis infections: four were genovar D,one was genovar G and one was genovar F. Conclusions: STIs are endemic in The Gambia. Monitoring systems should be established. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14712334
Volume :
23
Issue :
1
Database :
Academic Search Index
Journal :
BMC Infectious Diseases
Publication Type :
Academic Journal
Accession number :
164899513
Full Text :
https://doi.org/10.1186/s12879-023-08399-2