Plasma HIV-1 RNA Decline Within the First Two Weeks of Treatment Is Comparable for Nevirapine, Efaviranz, or Both Drugs Combined and Is Not Predictive of Long-Term Virologic Efficacy.

Authors :: van Leth, Frank
Huisamen, Casper B.
Badaro, Roberto
Vanderman, Bernard
de Wet, Joss
Montaner, Julio S. G.
Hall, David B.
Wit, Ferdinand W. N. M.
Lange, Joep M. A.
Source :: JAIDS: Journal of Acquired Immune Deficiency Syndromes. 3/1/2005, Vol. 38 Issue 3, p296-300. 5p. 3 Charts, 2 Graphs.
Publication Year :: 2005
Abstract: Cites a study from the U.S. which found a similar rate of initial decline of plasma HIV-1 RNA (pVL) for antiretroviral drugs Nevirapine, Efavirenz and its combination after adjusting for baseline pVL and region. Reasons to assess the rate of pVL decline; Relation between high viral decay constant and virological failure.

Subjects :: *PHARMACODYNAMICS
*ANTIRETROVIRAL agents
*HIV
*VIRAL load
*HIV infections
*AIDS

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