A Review on Nitroglycerin: Present and Future.

Nitroglycerin, a vasodilator, is typically used to treat anginal chest discomfort. The FDA currently approves it for the acute prophylaxis of angina pectoris owing to coronary artery disease (CAD) as well as the acute alleviation of an episode. The treatment of hypertensive urgency/emergency, coronary artery spasm, cocaine-related angina, congestive heart failure (CHF), and chronic anal fissures are a few of the unapproved, off-label uses for this medication. In order for medical professionals to successfully direct patient therapy in circumstances where nitroglycerin is advantageous to patient care, the present review describes the indications, mechanism of action, routes of administration, significant adverse effects, contraindications, monitoring, and toxicity of nitroglycerin. [ABSTRACT FROM AUTHOR]