Silver-mediated radical cascade cyclization of N-allylamides with sodium sulfinates to access sulfonated oxazolines.

A facile and practical silver-mediated radical cascade cyclization of N-allylamides with sodium sulfinates is developed, giving a series of sulfonated oxazolines in moderate to good yields. This transformation involves a radical process via intermolecular sulfonylation of alkenes and intramolecular cyclization. This reaction system could be also applied to access sulfonated dihydrofurans. [ABSTRACT FROM AUTHOR]