Back to Search Start Over

Fungal Vaccine Development: State of the Art and Perspectives Using Immunoinformatics.

Fungal Vaccine Development: State of the Art and Perspectives Using Immunoinformatics.

Authors :
Inácio, Moisés Morais
Moreira, André Luís Elias
Cruz-Leite, Vanessa Rafaela Milhomem
Mattos, Karine
Silva, Lana O'Hara Souza
Venturini, James
Ruiz, Orville Hernandez
Ribeiro-Dias, Fátima
Weber, Simone Schneider
Soares, Célia Maria de Almeida
Borges, Clayton Luiz
Source :
Journal of Fungi. Jun2023, Vol. 9 Issue 6, p633. 35p.
Publication Year :
2023

Abstract

Fungal infections represent a serious global health problem, causing damage to health and the economy on the scale of millions. Although vaccines are the most effective therapeutic approach used to combat infectious agents, at the moment, no fungal vaccine has been approved for use in humans. However, the scientific community has been working hard to overcome this challenge. In this sense, we aim to describe here an update on the development of fungal vaccines and the progress of methodological and experimental immunotherapies against fungal infections. In addition, advances in immunoinformatic tools are described as an important aid by which to overcome the difficulty of achieving success in fungal vaccine development. In silico approaches are great options for the most important and difficult questions regarding the attainment of an efficient fungal vaccine. Here, we suggest how bioinformatic tools could contribute, considering the main challenges, to an effective fungal vaccine. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
2309608X
Volume :
9
Issue :
6
Database :
Academic Search Index
Journal :
Journal of Fungi
Publication Type :
Academic Journal
Accession number :
164651115
Full Text :
https://doi.org/10.3390/jof9060633