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A practical flow synthesis of hydrazine derivatives from alcohols.
- Source :
-
New Journal of Chemistry . 6/28/2023, Vol. 47 Issue 24, p11394-11397. 4p. - Publication Year :
- 2023
-
Abstract
- Herein we demonstrate the application of continuous flow technology to the synthesis of hydrazine derivatives by deoxygenation of free alcohols with di-tert-butylazodicarboxylate. This operationally simple protocol has excellent functional group tolerance and enables large-scale synthesis and late-stage functionalization. It also provides access to three families of pharmacological compounds. [ABSTRACT FROM AUTHOR]
- Subjects :
- *HYDRAZINE derivatives
*ALCOHOL
*HYDRAZINE
*FUNCTIONAL groups
*DEOXYGENATION
Subjects
Details
- Language :
- English
- ISSN :
- 11440546
- Volume :
- 47
- Issue :
- 24
- Database :
- Academic Search Index
- Journal :
- New Journal of Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 164393786
- Full Text :
- https://doi.org/10.1039/d3nj02065g