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Outcomes in trauma patients undergoing veno-venous extracorporeal membrane oxygenation for acute respiratory distress syndrome.
- Source :
-
Perfusion . Jul2023, Vol. 38 Issue 5, p1037-1044. 8p. - Publication Year :
- 2023
-
Abstract
- Background: The use of veno-venous extracorporeal membrane oxygenation (VV ECMO) remains controversial in trauma patients with acute respiratory distress syndrome (ARDS). Here, we aimed to investigate the therapeutic benefits of VV ECMO and the factors affecting patient outcomes. Methods: From 2017 to 2019, 21/1938 trauma patients (median age: 47 years; 18 men) at a level I trauma center received VV ECMO for post-traumatic ARDS. Demographic, injury-specific, ECMO, and outcome data were prospectively collected and retrospectively reviewed to analyze the factors affecting hospital mortality and ECMO results. Results: 19 patients (90.5%) were successfully weaned off ECMO; 16 patients (76.2%) survived to discharge. In univariate analysis, there was a significant difference in survival between the groups with a Trauma and Injury Severity Score (TRISS) ⩾0.5 and TRISS <0.5 (p = 0.05). The area under the receiver operating characteristic curve (AUC) for both TRISS and Respiratory Extracorporeal Membrane Oxygenation Survival Prediction (RESP) scores for death was 0.78. In those who failed ECMO weaning, the AUCs of the TRISS and RESP scores were 0.90 and 0.80, respectively. Conclusions: In patients with ARDS caused by severe trauma and supported by VV ECMO, survival is associated with TRISS; TRISS and RESP scores may be predictive of mortality and failure in ECMO weaning. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ADULT respiratory distress syndrome treatment
*INJURY complications
*STATISTICS
*RESPIRATORY insufficiency
*CONFIDENCE intervals
*EXTRACORPOREAL membrane oxygenation
*RETROSPECTIVE studies
*PATIENTS
*ACQUISITION of data
*ADULT respiratory distress syndrome
*TREATMENT effectiveness
*HOSPITAL mortality
*ARTIFICIAL respiration
*EMERGENCY medical services
*MEDICAL records
*TRAUMA severity indices
*DESCRIPTIVE statistics
*GLASGOW Coma Scale
*RESEARCH funding
*RECEIVER operating characteristic curves
*VENTILATOR weaning
*DATA analysis software
*SENSITIVITY & specificity (Statistics)
*LONGITUDINAL method
*HYPOXEMIA
*PROPORTIONAL hazards models
*ADULTS
Subjects
Details
- Language :
- English
- ISSN :
- 02676591
- Volume :
- 38
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Perfusion
- Publication Type :
- Academic Journal
- Accession number :
- 164283738
- Full Text :
- https://doi.org/10.1177/02676591221093880