SARS-CoV-2 infection and viral fusogens cause neuronal and glial fusion that compromises neuronal activity.

The article discusses effect of structural and computational design severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and viral fusogens on neuronal activity. It mentions that SARS-CoV-2 infection induces fusion between neurons and glia in mouse and human brain organoids, where it mentions that neuronal fusion is a progressive and can lead to the formation of multicellular syncytia which further compromises neuronal activity.