Formulation Development and Evaluation of Anti acne Tazarotene & Hydroquinone Cream using novel excipients Rice bran wax.

Besides delivering drug to the body, a drug delivery system aims to improve patient compliance, patient acceptance. The dosage formsavailable for the delivery of topical agents include ointment, paste, CREAM, moisturizing cream and powder. However, cream is more preferabledue to their properties. Present research work is attempted to develop gel by using rice bran wax. Rice bran wax is the vegetable waxextracted from rice bran oil. The oil generally contains 2-6% wax. However it is assumed that on an average it contains 3% wax. Physicochemical tests such as globule size, evaluation of the intrinsic viscosity and homogeneity of cream products, have been traditionallyused to provide reasonable evidence of consistent product performance. However, for the purposes of these studies, the final cream productswere characterized for their clarity, pH, viscosity, spread ability, skin irritation test and in vitro diffusion studies using standard procedure. All the results match with official specifications. [ABSTRACT FROM AUTHOR]