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How effective is diluted povidone-iodine in preventing periprosthetic joint infection in total joint arthroplasty (TJA)? An updated systematic review and meta-analysis.
- Source :
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BMC Musculoskeletal Disorders . 5/25/2023, Vol. 24 Issue 1, p1-12. 12p. - Publication Year :
- 2023
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Abstract
- Purpose: Periprosthetic joint infection (PJI) is a serious complication with total joint arthroplasty (TJA), that necessitates reoperation. Pre-closure irrigation with dilute povidone-iodine (PI) is among the preventive measures, but its efficiency is still controversial. As a result, the focus of this systematic review and meta-analysis is on the effect of dilute PI wound irrigation in the prevention of PJI following TJA. Methods: We systematically reviewed and analyzed articles that compared PI with other agents in terms of PJI rate after TJA, searching Medline, Scopus, Web of science, and Cochrane databases. A number of 13 papers including 63,950 patients in total, were finally considered in qualitative and quantitative assessments. We have also further assessed review articles. Results: In comparison with normal saline (NS), PI reduced post-operative infection rate (OR: 0.44; CI 95%: 0.34–0.56). However, there was no difference between PI and chlorhexidine (CHG) (OR: 1.61; CI 95%: 0.83–3.09)) or undetermined comparators (OR: 1.08; CI 95%: 0.67–1.76). Conclusion: PI irrigation seems an efficient preventive measure for post-operative PJI and would seem to be the most feasible for TJA protocol. [ABSTRACT FROM AUTHOR]
- Subjects :
- *JOINT infections
*ARTHROPLASTY
*POVIDONE-iodine
*IRRIGATION (Medicine)
*REOPERATION
Subjects
Details
- Language :
- English
- ISSN :
- 14712474
- Volume :
- 24
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- BMC Musculoskeletal Disorders
- Publication Type :
- Academic Journal
- Accession number :
- 163913937
- Full Text :
- https://doi.org/10.1186/s12891-023-06548-x