Torsemide vs Furosemide After Discharge and All-Cause Mortality in Patients With Heart Failure—Reply.

TRANSFORM-HF set out to investigate a foundational question for the management of patients with heart failure and answered it (albeit with a neutral result). Effect of torsemide vs furosemide after discharge on all-cause mortality in patients hospitalized with heart failure: the TRANSFORM-HF randomized clinical trial. Comment & Response B In Reply b The TRANSFORM-HF investigators thank Dr Wolowich for his comments on our trial.[1] We appreciate his perspectives related to I CYP i sequence variants and a potential impact on torsemide metabolism. [Extracted from the article]