Serum vitamin D and cardiometabolic risk factors in the UK population.

We analysed data on 2842 subjects aged ≥40 years enrolled in the National Diet and Nutrition Survey (NDNS 2008–2019). Based on serum 25(OH)D concentrations, study subjects were grouped in three categories: vitamin D deficiency (<25 nmol/L), vitamin D insufficiency (25–49 nmol/L) and vitamin D sufficiency status (≥50 nmol/L). Differences in CVD risk factors between vitamin D deficiency or insufficiency and vitamin D sufficiency status were expressed in standard deviation scores (SDS) and estimated through weighted multiple linear regression models. Key points: Nationally representative data source UK National Diet and Nutrition Survey (2008–2019) is analysed.Vitamin D status is determined according to serum concentration of 25(OH)D deficiency: <25 nmol/L; insufficiency: 25–49 nmol/L; sufficiency: ≥50 nmol/L.Cardiovascular risk factors are compared between individuals with vitamin D deficiency and those with vitamin D sufficiency.Differences are expressed in standard deviation scores.Vitamin D deficiency is associated with a higher cardiovascular risk profile. [ABSTRACT FROM AUTHOR]