EV-D68 virus-like particle vaccines elicit cross-clade neutralizing antibodies that inhibit infection and block dissemination.

The article discusses about the virus-like particle (VLP) vaccines elicit a protective neutralizing antibody against homologous and heterologous Enter virus D68 (EV-D68) subclades. It further discusses that EV-D68 causes severe respiratory illness in children, result in a debilitating paralytic disease known as acute flaccid myelitis; and mentions that vaccine strain and adjuvant selection are critical elements for improving the breadth of protective immunity against EV-D68.