P*,N-Bidentate bicyclic phosphoramidite: synthesis and catalytic testing.

A new representative of novel chiral P*, N-bidentate bicyclic phosphoramidite ligands was synthesized. Palladium catalysts based on this ligand were tested in the asymmetric allylic alkylation of (E)-1,3-diphenylallyl acetate with dimethyl malonate and in the amination of the same substrate with pyrrolidine and demonstrated high activity (up to 100% conversion) and enantioselectivity up to 40% ee. [ABSTRACT FROM AUTHOR]