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New Approved Drugs Appearing in the Pharmaceutical Market in 2022 Featuring Fragments of Tailor-Made Amino Acids and Fluorine.

Authors :
Wang, Nana
Mei, Haibo
Dhawan, Gagan
Zhang, Wei
Han, Jianlin
Soloshonok, Vadim A.
Source :
Molecules. May2023, Vol. 28 Issue 9, p3651. 21p.
Publication Year :
2023

Abstract

The strategic fluorination of oxidatively vulnerable sites in bioactive compounds is a relatively recent, widely used approach allowing us to modulate the stability, bio-absorption, and overall efficiency of pharmaceutical drugs. On the other hand, natural and tailor-made amino acids are traditionally used as basic scaffolds for the development of bioactive molecules. The main goal of this review article is to emphasize these general trends featured in recently approved pharmaceutical drugs. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14203049
Volume :
28
Issue :
9
Database :
Academic Search Index
Journal :
Molecules
Publication Type :
Academic Journal
Accession number :
163686411
Full Text :
https://doi.org/10.3390/molecules28093651