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A Survey of Growth Hormone Stimulation Test Efficacy for Workup of Short Stature in a Referral Laboratory.
- Source :
-
Pakistan Armed Forces Medical Journal . Apr-Oct2009, Vol. 73 Issue 2, p477-477. 1p. - Publication Year :
- 2023
-
Abstract
- Objective: To assess growth hormone (GH) stimulation test efficacy in short stature workup for establishing GH deficiency. Study Design: Cross-sectional survey. Place and Duration of Study: Diagnostic Endocrine Section, Department of Chemical Pathology and Endocrinology, Armed Forces Institute of Pathology (AFIP), Rawalpindi Pakistan, from Aug 2020 to Jan 2021. Methodology: The study was conducted on 129 individuals aged 2-16 years. History, axiological data and biochemical parameters were assessed to establish GH deficiency for short stature workup. Results: Out of 129 individuals, 76(59%) boys and 53(41%) girls reported GH stimulation tests. 81(62.3%) children were in <3rd percentile, 29(22.3%) in <5th percentile, 9(6.9%) in <10th percentile and 5(3.8%) in <25th percentile. Among the group with bone age difference >2 years, 34(82.9%) fell in <3rd percentile. GH Stimulation test post-Levo Dopa was performed in 102(78.46%) patients. 49(37.4%) patients responded inadequately to the GH stimulation test. The adequate response to the GH Stimulation test improved as the percentile declined from the 50th to the 3rd percentile. Conclusion: GH stimulation test results can only partially rely upon though their importance remains in combination with other short-stature workup parameters for ruling out growth hormone deficiency. [ABSTRACT FROM AUTHOR]
- Subjects :
- *SHORT stature
*SOMATOTROPIN
*PITUITARY dwarfism
*AGE differences
*AGE groups
Subjects
Details
- Language :
- English
- ISSN :
- 00309648
- Volume :
- 73
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Pakistan Armed Forces Medical Journal
- Publication Type :
- Academic Journal
- Accession number :
- 163628486
- Full Text :
- https://doi.org/10.51253/pafmj.v73i2.7906